Determination of the concentration of cephalosporin antibiotics in blood by infrared spectroscopy

Abstract  We studied IR spectra of blood and cephalosporin antibiotics that are widely used in medical practice. We established the spectral regions that are suitable for determining their concentration in blood. It is shown using the antibiotic cephtriacson as an example that the IR spectroscopy method allows one to determine the concentrations of antibiotics in blood in the range of practical medical interest. We examined the possible transfer of antibiotics by blood erythrocytes.