Quantification of myocardial blood flow with 82Rb dynamic PET imaging

Abstract Purpose  The PET tracer 82Rb is commonly used to evaluate regional perfusion defects for the diagnosis of coronary artery disease. There is limited information on the quantification of myocardial blood flow and flow reserve with this tracer. The goal of this study was to investigate the use of a one-compartment model of 82Rb kinetics for the quantification of myocardial blood flow.