Ex vivo expansion of CD34+ cells and immunocytes from umbilical cord blood

Abstract Objective  Umbilical cord blood stem cell transplantation (CBSCT) has approached significant success in leukemia treatment, but it is associated with higher rates of delayed or failed engraftment and relapse. This may be caused by immature immune cells of umbilical cord blood. We try to expand stem/progenitor cells and T, NK, DC immunocytes from umbilical cord blood for transplantation and immunotherapy.